Efficacy testing - Biofilm Efficacy testing

Helle Stendahl Andersen

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Efficacy testing - Biofilm Efficacy testing

Danish Technological Institute offers biofilm efficacy testing of biocides, disinfectants, and antibiotics by using MBECTM Assay.

The MBECTM (Minimum Biofilm Eradication Concentration) Assay is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of Pseudomonas aeruginosa, and a variety of other microorganisms.

With this test, it is possible to test a variety of disinfecting agents at the same time or to test several different concentrations of the same product.

Biofilms are a group of microorganisms that can stick together to a surface embedded in a matrix of organic material / substance or mucus.

Biofilm is typically created when bacteria absorb to a surface, where there is a lot of organic material is present. Biofilm exist on almost all surfaces, e.g., in distribution systems, equipment for food, dental equipment, medical devices, artificial joints and catheters.

Microorganisms that have formed biofilms are difficult to remove, because biofilm has a greater tolerance to biocides than microorganisms, which are not bound in biofilm. Therefore it is necessary to carry out biofilm efficacy testing to be sure that the product possess the desired effect.

How can Danish Technological Institute help you?

We i.a. offer the following:

  • Efficacy testing of disinfectants and other biocidal products against biofilm using MBECTM Assay
  • Screening of biocides and disinfectants
  • Screening of different concentrations from one or more products
  • Develop a a method for the relevant type of biofilm